1997 336:933-8.Anemia is when your blood has too few red blood cells. Erythropoietin treatment of anemia associated with multiple myeloma. Ludwig H, Fritz E, Kotzmann H, Hocker P, Gisslinger H, Barnas U. Erythropoietin and the anaemia of chronic disease. Multicenter study of recombinant human erythropoietin in correction of anemia in rheumatoid arthritis. Pincus T, Olsen NJ, Russell IJ, Wolfe F, Harris ER, Schnitzer TJ, et al. Bone marrow biopsy findings in childhood anemia: prevalence of transient erythroblastopenia of childhood. Improved approach to patients with normocytic anemia. Continuation of decline in prevalence of anemia in low-income children: the Vermont experience. New York: McGraw-Hill, Health Professions Division, 1995:709–14. Human cardiovascular and metabolic response to acute, severe isovolemic anemia. Weiskopf RB, Viele MK, Feiner J, Kelley S, Lieberman J, Noorani M, et al. Physiologic effects of acute anemia: implications for a reduced transfusion trigger. Levine E, Rosen A, Sehgal L, Gould S, Sehgal H, Moss G. Baltimore: Williams &Wilkins, 1999:908–40.Ībramson SD, Abramson N. New York: Churchill Livingstone, 2000:383–8. Hematology: basic principles and practice. Pathogenesis and treatment of the anemia of chronic disease. The definition of anemia in older persons. Prevalence of anemia in medical practice: community versus referral patients. (PHS) 95–1521.Īnia BJ, Suman VJ, Fairbanks VF, Melton LJ. Series 10: Data from the National Health Survey no. of Health and Human Services, Public Health Service, Centers for Disease Control, National Center for Health Statistics, 1995. Current estimates from the National Health Interview Survey, 1994. New York: Churchill Livingstone, 2000:367–82.Īdams PF, Marano MA. Approach to the adult and child with anemia. Schnall SF, Berliner N, Duffy TP, Benz EF Jr. Improved classification of anemias by MCV and RDW. Percentile curves for hemoglobin and red cell volume in infancy and childhood. Sucrose hemolysis (screening) Ham's test (confirmatory)ĭallman PR, Siimes MA. Recurrent abdominal pain, vomiting, headache, eye pain venous thromboses leads to iron deficiency anemia Mild to moderate anemia frequently, iron deficiency, second-degree chronic urinary loss history of heart valve replacement or valvular disease Purpura, fever, central nervous system changes generally occurs in adults Hypofibrinogenemia increases in partial thromboplastin time, prothrombin time, fibrin split products and thrombin timeįever, jaundice, bleeding, central nervous system changes, renal failure generally occurs in children Red blood cell P-50 level (screening) red blood cell pyruvate kinase activity (confirmatory) Variable: severe anemias in newborns to no symptoms in adults Transient hemolysis following exposure to oxidative drug Variable: asymptomatic carrier state to severe hemolysisĢ5 percent or more of red blood cells elliptocytic on peripheral blood smear Generally similar to homozygous sickle cell disease, except associated with fewer infections, less hemolysis and fewer crises, but more retinopathy and aseptic necrosis Vaso-occlusive crises, splenomegaly, cerebrovascular accidents, priapism, hand-foot syndrome, acute chest syndrome Glucose-6-phosphate dehydrogenase deficiency Heterozygous sickle hemoglobin C disease (hemoglobin SC disease) Homozygous sickle cell disease (hemoglobin SS disease) Increased red blood cell loss or destruction
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